Anti-Cytochrome C [E8]
Ab02837-23.0
ApplicationsRadioImmunoAssay
Product group Antibodies
ReactivityEquine
Overview
- SupplierAbsolute Antibody
- Product NameAnti-Cytochrome C [E8]
- Delivery Days Customer7
- Antibody SpecificityThis antibody binds horse cytochrome c. This antibody recognizes three major discontiguous segments (33 to 39; 56 to 66; 96 to 104), and two minor sites on cyt c opposite to the exposed haem edge (PMID: 9698550).
- Application Supplier NoteThe original mouse IgG1 version of this antibody binds horse cytochrome c with an affinity of Kd ~ 10(-9) M (PMID: 2993413). A solid phase radioimmunoassay was used to identify the specific epitope that the antibody binds (PMID: 2454225). The structural mechanism involved in the binding of the IgG1 antibody E8 to its highly charged protein antigen horse cytochrome c (cyt c) was studied using crystallographic structures (PMID: 9698550).
- ApplicationsRadioImmunoAssay
- Applications SupplierRIA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDE8
- HostRabbit
- IsotypeIgG
- Protein IDP00004
- Protein NameCytochrome c
- Scientific DescriptionThis chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
- ReactivityEquine
- Reactivity SupplierHorse (Equus caballus)
- Reactivity Supplier NoteThe original antibody was generated by immunizing BALB/c mice with horse cytochrome c (cyt c) conjugated to hemocyanin.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203