Anti-Cytokeratin 5/6 [AbM58019-7H4]

Absolute Antibody

Anti-Cytokeratin 5/6 [AbM58019-7H4]

9

This antibody is capable of binding human cytokeratin 5 and human cytokeratin 6. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin 5/6 is often expressed in a basal cell layer of normal ma

The binding characterization of this antibody was done using ELISA. The original IgG2b antibody binds cytokeratin 5/6 with a high affinity constant of 3.84 x 10^(9) M^(-1). This antibody was also used in the immunohistochemical analysis of esophagus and esophageal squamous cell carcinoma. The immunohistochemical staining pattern of this antibody is similar to commercially available antibody D5/16B4 (CN113845592).

ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

AbM58019-7H4

KRT5

keratin 5

58 kda cytokeratin; CK5; CK-5; cytokeratin-5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin, type II cytoskeletal 5; KRT5A; type-II keratin Kb5

Human

IgG1

Keratin, type II cytoskeletal 5

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

Human

-20°C,2°C to 8°C

12352203