anti-DBC1 antibody

Arigo Biolaboratories

anti-DBC1 antibody

23

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

1 mg/ml

Unconjugated

CCAR2

cell cycle and apoptosis regulator 2

cell cycle and apoptosis regulator protein 2; cell division cycle and apoptosis regulator protein 2; DBC1; DBC-1; deleted in breast cancer 1; KIAA1967; NET35; p30 DBC; p30DBC

Mouse

IgG1

Core component of the DBIRD complex,a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing:the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions.Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis.Inhibits SUV39H1 methyltransferase activity.As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.

Human

-20°C

12352203