anti-Decorin antibody [DCN/3523]

Arigo Biolaboratories

anti-Decorin antibody [DCN/3523]

23

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

DCN/3523

0.2 mg/ml

Unconjugated

DCN

decorin

bone proteoglycan II; CSCD; decorin; dermatan sulphate proteoglycans II; DSPG2; PG40; PGII; PGS2; proteoglycan core protein; SLRR1B; small leucine-rich protein 1B

Mouse

IgG2b

This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]

Human

-20°C

12352203