Anti-desmocollin-2/3 [7G6]

Absolute Antibody

Anti-desmocollin-2/3 [7G6]

9

This antibody recognizes desmocollin-2 (also known as Desmocollin-3). Desmocollins (next to desmogleins) are the main desmosomal transmembrane proteins.The expression of desmocollin-2 varies in the basal and suprabasal layers.

The antibody 7G6 is recommended for the detection and analysis of desmocollin-2 (desmocollin-3) via various methods, such as immunohistochemistry, Western blot and others. For instance, the antibody was used to label desmocollin-2 in primary human keratinocytes via immunohistochemistry (Franke et al., 2006). Similarly, another group detected desmocollin-2 in A431 cells (Wahl et al., 2005). The antibody 7G6 was also utilized in the assessment of expression levels of desmocollin-2 in SHEEC and KYSE510 cells via Western blot (Fang et al., 2014).

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoHistoChemistry

Research Use Only

Monoclonal

7G6

DSC2

desmocollin 2

ARVD11; cadherin family member 2; CDHF2; desmocollin-2; desmosomal glycoprotein II/III; DG2; DGII/III; DSC3

Rabbit

IgG

Desmocollin-2

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human, Mouse, Rat

-20°C,2°C to 8°C

12352203