Anti-desmoglein-2 [6D8]

Absolute Antibody

Anti-desmoglein-2 [6D8]

9

This antibody recognizes human desmoglein-2. This clone does not cross-react with Desmoglein 1 or Desmoglein 3. The epitope is within the extracellular domain (EC3/EC4) of Desmoglein 2/DSG2. Desmoglein-2 is part of a cadherin protein family and is involve

The antibody 6D8 has been used successfully to identify and analyse desmoglein-2 via various methods. For instance, it was utilized to label desmoglein 2 in melanoma tissue samples via immunohistochemistry to investiagete expression pattern of DSG2 in this cancer (Tan et al., 2016; pmid: 27340778). Furthermore, this antibody was also used to label DSG2 during flow cytometric analysis of cells (Tan et al., 2016; pmid: 27340778). The antibody 6D8 has also been applied in a Western blot detection of desmogleins in transfected A-431D cells (Wahl, 2002; pmid: 11991815). Finally, this antibody immunoprecipitated desmoglein-a from A-431 cell extracts prepared in 0.1% Empigen BB (Wahl, 2002; pmid: 11991815).

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

6D8

DSG2

desmoglein 2

cadherin family member 5; CDHF5; desmoglein-2; HDGC

Mouse

IgG1

Desmoglein-2

Human

-20°C,2°C to 8°C

12352203