Anti-desmoglein-3 [5G11]

Absolute Antibody

Anti-desmoglein-3 [5G11]

9

This antibody recognizes desmoglein 3. It does not cross-react with desmoglein 1 or desmoglein 2. Desmoglein-3 is a calcium binding membrane protein that is localized in desmosome cellular junctions and interacts with plaque proteins and intermediate fila

This antibody can be used for detection and analysis of desmoglein-3 via various methods. For instance, 5G11 was utilized todetect desmoglein-3 in human scalp hair follicles and epidermal inclusions via immunohistochemistry (Wu et al., 2003). Another group successfully used this antibody to identify desmoglein-3 via Western blot (Mao et al., 2017; pmid: 28469076). The antibody 5G11 was also used to detect DSG3 in cells via immunofluorescence (Chen et al., 2013; pmid: 23737966).

Dot Blot, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

5G11

DSG3

desmoglein 3

130 kDa pemphigus vulgaris antigen; ABOLM; cadherin family member 6; CDHF6; desmoglein-3; PVA

Rabbit

IgG

Desmoglein-3

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203