anti-Dispatched homolog 1 antibody

Arigo Biolaboratories

anti-Dispatched homolog 1 antibody

23

ImmunoFluorescence, ImmunoCytoChemistry

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

DISP1

dispatched RND transporter family member 1

DISPA; dispatched A; protein dispatched homolog 1

Goat

IgG

The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008]

Human, Mouse, Porcine, Rat

-20°C

12352203