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anti-DMPO Nitrone Adduct antibody [N166A4] (FITC)

ARG20540
Arigo Biolaboratories
ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-DMPO Nitrone Adduct antibody [N166A4] (FITC)
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    N1664A
  • Concentration
    0.48 mg/ml
  • Conjugate
    FITC
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    The formation of free radicals and other highly reactive oxygen species has been implicated in the pathogenesis of many disease states. The ability to identify these species is crucial, and spin trapping has accomplished this goal. DMPO (5,5-dimethyl-1-pyrroline N-oxide) is one of the least toxic to cells and animals, and possesses convenient pharmacokinetics (uptake, distribution, metabolism and excretion) in biological systems. Recent studies have determined that nitric oxide may substantially affect the quantitative determination of DMPO adducts, and therefore extra caution is required when studying generation of these species in the presence of nitric oxide or its radicals. DMPO adducts can be generated with protein and DNA radicals.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203