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anti-Dnmt3L antibody [S117-9]

ARG22285
Arigo Biolaboratories
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetDNMT3L
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Dnmt3L antibody [S117-9]
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    S117-9
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID29947
  • Target name
    DNMT3L
  • Target description
    DNA methyltransferase 3 like
  • Target synonyms
    cytosine-5-methyltransferase 3-like protein; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; human cytosine-5-methyltransferase 3-like protein
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203