Anti-DOG1 [19F2]

Absolute Antibody

Anti-DOG1 [19F2]

7

The antibody is specific for DOG1. DOG1 is a calcium-activated chloride channel (CaCC) which plays a role in the transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (I

The antibody 19F2 and the commercial antibody SP31 were used to stain breast tissue and gastrointestinal tumor in immunohistochemistry. Results showed the antibody specificity is equivalent to the commercial antibody. Further, the staining intensity of the antibody 19F2 was higher than the commercial antibody (CN113045652A).

Western Blot, ELISA, ImmunoHistoChemistry

IHC; WB; ELISA

Research Use Only

Monoclonal

19F2

ANO1

anoctamin 1

anoctamin 1, calcium activated chloride channel; anoctamin-1; Ca2+-activated Cl- channel; calcium activated chloride channel; discovered on gastrointestinal stromal tumors protein 1; DOG1; oral cancer overexpressed 2; ORAOV2; TAOS2; TMEM16A; transmembrane protein 16A (eight membrane-spanning domains); tumor-amplified and overexpressed sequence 2

Human

IgG1

Anoctamin-1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

Human

Human

The original antibody was generated by immunizing mice with recombinant protein DOG1.

-20°C,2°C to 8°C

12352203