Immunofluorescence: cultured rat neurons showing strong cytoplasmic staining of doublecortin (green)(ARG52266) in developing neurons and GFAP (ARG52313) in red.
![Immunofluorescence: Cortical neuron-glial cell culture from E20 Rat stained with ARG52266 anti-Doublecortin antibody [3 e1] (red) at 1:1000 dilution, and costained with anti-MAP2 antibody (green) at 1:10000 dilution. DAPI (blue) for nuclear staining.](https://www.arigobio.com/files/product/5113/ARG52266_IF_1_191002.jpg "Immunofluorescence: Cortical neuron-glial cell culture from E20 Rat stained with ARG52266 anti-Doublecortin antibody [3 e1] (red) at 1:1000 dilution, and costained with anti-MAP2 antibody (green) at 1:10000 dilution. DAPI (blue) for nuclear staining.")
![Western blot: Adult Rat brain (negative control) and embryonic E20 Rat brain lysates stained with ARG52266 anti-Doublecortin antibody [3 e1] (green) at 1:1000 dilution.](https://www.arigobio.com/files/product/5113/ARG52266_WB_1_191002.jpg "Western blot: Adult Rat brain (negative control) and embryonic E20 Rat brain lysates stained with ARG52266 anti-Doublecortin antibody [3 e1] (green) at 1:1000 dilution.")
Immunofluorescence: cultured rat neurons showing strong cytoplasmic staining of doublecortin (green)(ARG52266) in developing neurons and GFAP (ARG52313) in red.
anti-Doublecortin antibody [3 e1]
ARG52266
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman
TargetDCX
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Doublecortin antibody [3 e1]
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3 e1
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1641
- Target nameDCX
- Target descriptiondoublecortin
- Target synonymsDBCN; DC; doublecortex; doublin; lissencephalin-X; LISX; lis-X; neuronal migration protein doublecortin; SCLH; XLIS
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionDoublecortin, or DCX, is a microtubule associated protein that is expressed almost exclusively in very early neuronal development (Brown et al., 2003), making it an excellent marker for developing neuronal cells. Defects in the DCX gene lead to X-linked lissencephaly which is characterized by a lack of normal folds on the surface of the brain resulting in a smooth cerebral cortex caused by abnormal migration of neurons during development (des Portes et al., 1998; Gleeson et al., 1998).
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203