Anti-DPGA anthrax [F24F2]

Absolute Antibody

Anti-DPGA anthrax [F24F2]

9

This antibody specifically binds the poly-gamma-D-glutamic acid (gammaDPGA) capsule of Bacillus anthracis. Bacillus anthracis is surrounded by an antiphagocytic polypeptide capsule composed of poly gamma-d-glutamic acid (gammaDPGA). The gammaDPGA capsule

This antibody was used for development of a quantitative capture ELISA for PDGA (PMID: 18195035). A 50:50 mixture of PDGA antibodies F24F2 and F26G3 was used in the development of an antigen capture ELISA with a sensitivity of approximately 9 ng/ml of serum after a 1/40 dilution and 2.25 ng/ml for a 1:10 dilution (PMID: 19506008). The HRP or Alexa Fluor 555 labelled antibody was also used in the immunohistochemical staining of gammaDPGA in mouse liver and spleen tissues after they were injected with 500, 100, or 20microg of gammaDPGA and tissues were harvested on days 1, 2, 4, and 8 (PMID: 18195035). This antibody was also used in the cellular localization of gammaDPGA in mouse liver (PMID: 18195035).

ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry

Research Use Only

Monoclonal

F24F2

Rabbit

IgG

Bacteria

-20°C,2°C to 8°C

12352203