anti-DPYD antibody

Arigo Biolaboratories

anti-DPYD antibody

23

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

DPYD

dihydropyrimidine dehydrogenase

DHP; DHPDHASE; dihydropyrimidine dehydrogenase [NADP(+)]; dihydrothymine dehydrogenase; dihydrouracil dehydrogenase; DPD

Rabbit

IgG

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Human

-20°C

12352203