Anti-DR5 [304]

Absolute Antibody

Anti-DR5 [304]

9

The antibody is specific to human DR5.

This antibody has shown high anti-tumour activity in mice with subcutaneously transplanted colon carcinoma cells Colo205. It has tumour-specific cell-death-inducing activity alone in tissue culture so is expected to show anti-tumour activity independent of physiological conditions of the patient. The antibody has been shown to function in ELISA and RIA.

ELISA, RadioImmunoAssay

Research Use Only

Monoclonal

304

TNFRSF10B

TNF receptor superfamily member 10b

apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; DR5; Fas-like protein; KILLER; KILLER/DR5; p53-regulated DNA damage-inducible cell death receptor(killer); TNF-related apoptosis-inducing ligand receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; ZTNFR9

Human

IgG4

Tumor necrosis factor receptor superfamily member 10B

This reformatted human antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203