Anti-E-protein [DV22]

Absolute Antibody

Anti-E-protein [DV22]

7

DV22 has been used in cell-based assays and was shown to exhibit neutralisation and antibody-dependent enhancing activity using Vero and K562 cells (Beltramello et al, 2010). This antibody has also been characterised as EDI/II-specific by ELISA and Western blot. When generated as a LALA variant and supplied as a cocktail with two other anti-DENV mAbs, DV22 showed a complete lack of antibody-dependent enhancement (ADE) activity, whilst retaining the ability to neutralise DENV infection.

Flow Cytometry, Western Blot, ELISA, Neutralisation/Blocking

ELISA; NTRL; WB; FC

Research Use Only

This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203