Anti-E-protein [DVC21]

Absolute Antibody

Anti-E-protein [DVC21]

9

This antibody recognises domain III of the DENV envelope (E) protein. It has been shown that DVC21 is cross-reactive to all 4 DENV serotypes.

DVC21 has been used in cell-based assays and was shown to exhibit both neutralisation and antibody-dependent enhancing activity using primary human monocytes (Kou et al, 2011). This antibody has also been characterised as EDIII-specific by ELISA and Western blot (Beltramello et al, 2010).

Flow Cytometry, Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

DVC21

Rabbit

IgG

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203