anti-EGLN1 / PHD2 antibody
![Research Use Only](static/images/certificates/ruo.jpg)
ARG41897
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetEGLN1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-EGLN1 / PHD2 antibody
- Delivery Days Customer23
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID54583
- Target nameEGLN1
- Target descriptionegl-9 family hypoxia inducible factor 1
- Target synonymsC1orf12; ECYT3; egl nine homolog 1; egl nine-like protein 1; HALAH; HIFPH2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH2; HPH-2; hypoxia-inducible factor prolyl hydroxylase 2; PHD2; prolyl hydroxylase domain-containing protein 2; SM20; zinc finger MYND domain-containing protein 6; ZMYND6
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203