Anti-EME1 [7h2/1]

Absolute Antibody

Anti-EME1 [7h2/1]

9

This antibody recognises human EME1. EME1 together with MUS81 create a DNA endonuclease which binds preferentially to branched DNA structures such as Holliday junctions and replication forks. Its engaged in processing of stalled or collapsed replication f

WB: MTA31 7h2/1 antibody was used to detect EME1 in western blot analysis in the experiments assessing EME1 as a potential marker of cisplatin resistance in cancer therapy (Tomoda et al., 2009). WB: This antibody was used to detect EME1 on western blots after previous immunopurification procedure (Laguette et al., 2014). IHC: Other group conducted an immunohistochemistry experiment staining against EME1 in formalin-fixed paraffin embedded esophageal adenocarcinoma tissue samples using MTA31 7h2/1 antibody (Dwalt et al., 2014).

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

7h2/1

EME1

essential meiotic structure-specific endonuclease 1

crossover junction endonuclease EME1; essential meiotic endonuclease 1 homolog 1; essential meiotic endonuclease 1 homolog 2; hMMS4; homolog of yeast EME1 endonuclease; MMS4 homolog; MMS4L; SLX2 structure-specific endonuclease subunit homolog A; SLX2A

Mouse

Crossover junction endonuclease EME1

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203