Anti-Envelope protein (soluble) [Z20]

Absolute Antibody

Anti-Envelope protein (soluble) [Z20]

7

Z20 was confirmed to bind ZIKV sE protein by ELISA, with an affinity of 0.16 uM shown by SPR (Wang et al, 2016). Using a FACS-based assay, it was shown that Z20 potently neutralised viral activity against infected C6/36 and Vero cells. In vivo, Z20 was able to protect 80% of IFN receptor KO mice from ZIKV infection.

Flow Cytometry, ELISA, Neutralisation/Blocking, Other Application

NTRL; crystallisation; ELISA; FC; SPR

Research Use Only

This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203