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anti-Estrogen Receptor alpha antibody [SQab1889]

Research Use Only
ARG66356
Arigo Biolaboratories
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetESR1
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Estrogen Receptor alpha antibody [SQab1889]
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SQab1889
  • Conjugate
    Unconjugated
  • Gene ID2099
  • Target name
    ESR1
  • Target description
    estrogen receptor 1
  • Target synonyms
    E2 receptor alpha; ER; Era; ER-alpha; ESR; ESRA; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; ESTRR; NR3A1; nuclear receptor subfamily 3 group A member 1; oestrogen receptor alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203