Anti-F protein [mAb 234]

Absolute Antibody

Anti-F protein [mAb 234]

9

This antibody recognizes the hMPV F protein in the helix-loop-helix motif within site II. Human metapneumovirus (hMPV) is a member of the Paramyxoviridae family/Pneumovirinae subfamily and shares many common features with respiratory syncytial virus (RSV)

ELISA was used to confirm the binding of this antibody to hMPV F protein. This antibody has been reported to have high neutralizing activity against all of the hMPV types A1, A2, B1, and B2 with an in vitro IC50 of < 2microg/ml. The antibody is effective as passive prophylaxis, protecting hamsters and mice from hMPV challenge (PMID: 16873237).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

mAb 234

Mouse

IgG1

Fusion glycoprotein F0

Virus

-20°C,2°C to 8°C

12352203