Anti-Factor H binding protein [clone4]

Absolute Antibody

Anti-Factor H binding protein [clone4]

9

This antibody binds a surface exposed epitope on N. meningitidis FHbp, a virulence factor critical for surviving of the bacteria in the human host. FHbp protein is a bacterial surface lipoprotein that binds host (human) complement factor H (fH, gene CFH).

This antibody exhibited high affinity and specificity in the enzyme-linked immunosorbent assay (ELISA) and the whole bacterial cell enzyme-linked immunosorbent assay (Bact-ELISA). The binding affinity of the scFv version of this antibody for fHbp was reported to be Kd= 7.03 nM (PMID: 29737965).

ELISA

Research Use Only

Monoclonal

clone4

Rabbit

IgG

Bacteria

-20°C,2°C to 8°C

12352203