Bio-Connect

anti-Factor VIII antibody [RFF-VIIIC/8]

ARG22573
Arigo Biolaboratories
ApplicationsWestern Blot, ELISA, RadioImmunoAssay
Product group Antibodies
ReactivityHuman
TargetF8
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Factor VIII antibody [RFF-VIIIC/8]
  • Delivery Days Customer
    23
  • Applications
    Western Blot, ELISA, RadioImmunoAssay
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RFF-VIIIC/8
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2157
  • Target name
    F8
  • Target description
    coagulation factor VIII
  • Target synonyms
    AHF; antihemophilic factor; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIIIc; DXS1253E; F8B; F8C; factor VIII F8B; FVIII; HEMA
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203