Anti-Factor VIII:c light chain [RFF-VIII:c/5]

Absolute Antibody

Anti-Factor VIII:c light chain [RFF-VIII:c/5]

9

This antibody is specific for a C-terminal site on human coagulation factor VIII

This antibody is a coagulation inhibitor, though displays only weak anticoagulant activity (Rotblat et al, 1983). It has been used as the solid-phase immunoadsorbent in a two-site immunoradiometric assay of Factor VIII:c (Rotblat et al, 1983).When bound to Sepharose columns, this antibody has been used to deplete factor VII:c from plasma through column chromatography (Takase et al, 1987).

IRMA ImmunoRadioMetric Assay, Neutralisation/Blocking

Research Use Only

Monoclonal

RFF-VIII:c/5

F8

coagulation factor VIII

AHF; antihemophilic factor; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIIIc; DXS1253E; F8B; F8C; factor VIII F8B; FVIII; HEMA

Human

IgG1

Coagulation factor VIII

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203