anti-FADD antibody

Arigo Biolaboratories

anti-FADD antibody

23

ImmunoPrecipitation, Western Blot

Research Use Only

Monoclonal

1 mg/ml

Unconjugated

FADD

Fas associated via death domain

Fas (TNFRSF6)-associated via death domain; FAS-associated death domain protein; Fas-associating death domain-containing protein; Fas-associating protein with death domain; GIG3; growth-inhibiting gene 3 protein; mediator of receptor-induced toxicity; MORT1

Mouse

IgG1

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors.The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation.Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.Involved in interferon-mediated antiviral immune response,playing a role in the positive regulation of interferon signaling.

Human

-20°C

12352203