Anti-Ferritin H [4C9]

Absolute Antibody

Anti-Ferritin H [4C9]

9

This antibody binds human acidic isoferritin. Ferritin is a protein that catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis. Ferritins

The binding specificity of this antibody towards acidic isoferritin, basic isoferritin and human liver ferritin was determined using ELISA. This antibody does not cross react with basic isoferritin and human liver ferritin. The binding affinity of the original mouse IgG1 format of this antibody for acidic isoferritin was reported to be Kd= 4.15 nM. This antibody was used for the immunohistochemical staining of liver tissues of primary hepatic carcinoma (PHC)(PMID: 11604110). This antibody can be used for the identification of acidic isoferritins in a western blot (PMID: 12697395).

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

4C9

FTH1

ferritin heavy chain 1

apoferritin; cell proliferation-inducing gene 15 protein; ferritin H subunit; ferritin heavy chain; ferritin, heavy polypeptide 1; FHC; FTH; FTHL6; HFE5; PIG15; placenta immunoregulatory factor; PLIF; proliferation-inducing protein 15

Human

IgG1

Ferritin heavy chain

This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203