anti-FH / Fumarase antibody [3F6]
ARG57146
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetFH
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-FH / Fumarase antibody [3F6]
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3F6
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2271
- Target nameFH
- Target descriptionfumarate hydratase
- Target synonymsepididymis secretory sperm binding protein; FMRD; fumarase; fumarate hydratase, mitochondrial; HLRCC; HsFH; LRCC; MCL; MCUL1
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionThe protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203