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anti-FH / Fumarase antibody [3F6]

Research Use Only
ARG57146
Arigo Biolaboratories
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetFH
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-FH / Fumarase antibody [3F6]
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    3F6
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2271
  • Target name
    FH
  • Target description
    fumarate hydratase
  • Target synonyms
    epididymis secretory sperm binding protein; FMRD; fumarase; fumarate hydratase, mitochondrial; HLRCC; HsFH; LRCC; MCL; MCUL1
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203