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anti-Fibrinogen antibody [49D2]

ARG10369
Arigo Biolaboratories
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetFGA
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Fibrinogen antibody [49D2]
  • Delivery Days Customer
    23
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    49D2
  • Concentration
    1.0-2.0 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2243
  • Target name
    FGA
  • Target description
    fibrinogen alpha chain
  • Target synonyms
    Fib2; fibrinogen alpha chain; fibrinogen, A alpha polypeptide
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203