anti-Fibrinogen antibody [49D2]

Arigo Biolaboratories

anti-Fibrinogen antibody [49D2]

23

Western Blot, ELISA

Research Use Only

Monoclonal

49D2

1.0-2.0 mg/ml

Unconjugated

FGA

fibrinogen alpha chain

Fib2; fibrinogen alpha chain; fibrinogen, A alpha polypeptide

Mouse

IgG2a

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203