anti-Fibrinogen antibody [49D2]
ARG10369
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetFGA
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Fibrinogen antibody [49D2]
- Delivery Days Customer23
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID49D2
- Concentration1.0-2.0 mg/ml
- ConjugateUnconjugated
- Gene ID2243
- Target nameFGA
- Target descriptionfibrinogen alpha chain
- Target synonymsFib2; fibrinogen alpha chain; fibrinogen, A alpha polypeptide
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionThe protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203