Anti-Flagellin protein [0A07], Rabbit IgG-Fc Fusion,

Absolute Antibody

Anti-Flagellin protein [0A07], Rabbit IgG-Fc Fusion,

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This antibody is specific for the flagellin protein (FliC) of Salmonella enterica, which plays a pivotal role in bacterial motility and pathogenicity. FliC is the main structural component of the bacterial flagella in Salmonella enterica, tail-like struct

The original version of this antibody (alpaca VHH) exhibited the highest inhibition of intracellular S. enterica (strain Hadar 5643) growth out of all of the tested antibodies. In vitro, the antibody was evaluated for its ability to disrupt Salmonella colonization in chicken intestinal cultures, resulting in a significant 7.5-log reduction in Salmonella genome copy numbers in ileum sections. In vivo, it was tested for its protective efficacy in broiler chickens challenged with Salmonella enterica via oral gavage. The antibody significantly decreased Salmonella levels by 0.7 log10 in both jejunum and ileum compared to the control group when administered at three different time points post-challenge (US10421806B2).

ELISA, Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

0A07

Rabbit

IgG

This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.

Bacteria

-20°C,2°C to 8°C

12352203