Immunohistochemistry: Frozen section of adult rat hippocampus tissue stained with ARG11144 anti-FOX3 / NeuN antibody (red) at 1:2000 dilution, and co-stained with ARG10719 anti-MAP2 antibody [4H5] (green) at 1:2000 dilution. DAPI (blue) for nuclear staining. (Sample preparation: Following transcardial perfusion of mouse with 4% paraformaldehyde, brain was post fixed for 24 hours, cut to 45 microM, and free-floating sections were stained with the above antibodies.).
anti-FOX3 / NeuN antibody
ARG11144
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman
TargetRBFOX3
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-FOX3 / NeuN antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID146713
- Target nameRBFOX3
- Target descriptionRNA binding fox-1 homolog 3
- Target synonymsfox-1 homolog C; FOX3; FOX-3; hexaribonucleotide binding protein 3; HRNBP3; NEUN; neuN antigen; neuronal nuclei antigen; RNA binding protein fox-1 homolog 3; RNA binding protein, fox-1 homolog 3
- HostGoat
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203