Anti-GABA-A Receptor, Gamma 2 Subunit [10F10-C1-B8]

Absolute Antibody

Anti-GABA-A Receptor, Gamma 2 Subunit [10F10-C1-B8]

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In the original study, this antibody was used in Western Blot assays, immunohistochemistry (IHC) and immunoprecipitate (IP) for identification of the gamma2 subunit from rat and mouse hippocampal proteins (Joshi et al., 2011). This antibody could also be used in functional studies, for example, to show that the GABA-A receptor membrane insertion rates are specified by their subunit composition (Joshi et al, 2013), to delineate how chorein deficiency leads to upregulation of gephyrin and GABAA receptor (Kurano et al., 2006), to examine the homeostatic strengthening of inhibitory synapses as mediated by the accumulation of GABAA receptors (Rannals et al., 2011), and to demonstrate that NMDA receptor activation downregulates expression of delta Subunit-containing GABA-A receptors in cultured hippocampal neurons (Joshi et al. 2013).

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

WB; IF; IHC; IP

Research Use Only

Gamma-aminobutyric acid receptor subunit gamma-2

-20°C,2°C to 8°C

12352203