anti-GAT2 / GABA Transporter 2 antibody

Arigo Biolaboratories

anti-GAT2 / GABA Transporter 2 antibody

23

ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Slc6a13

solute carrier family 6 member 13

GAT-2; sodium- and chloride-dependent GABA transporter 2; solute carrier family 6 (neurotransmitter transporter), member 13; solute carrier family 6 (neurotransmitter transporter, GABA), member 13

Rabbit

IgG

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by highaffinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999).

Mouse, Rat

-20°C

12352203