anti-GCK / Germinal Center Kinase antibody

Arigo Biolaboratories

anti-GCK / Germinal Center Kinase antibody

23

Western Blot

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

MAP4K2

mitogen-activated protein kinase kinase kinase kinase 2

B lymphocyte serine/threonine protein kinase; BL44; GCK; germinal centre kinase (GC kinase); MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; mitogen-activated protein kinase kinase kinase kinase 2; Rab8 interacting protein; RAB8IP

Rabbit

IgG

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Human

-20°C

12352203