anti-GDNF antibody (Biotin)
ARG56798
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetGDNF
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-GDNF antibody (Biotin)
- Delivery Days Customer23
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateBiotin
- Gene ID2668
- Target nameGDNF
- Target descriptionglial cell derived neurotrophic factor
- Target synonymsastrocyte-derived trophic factor; ATF; ATF1; ATF2; glial cell line-derived neurotrophic factor; HFB1-GDNF; HSCR3
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203