Anti-gH [YC15]

Absolute Antibody

Anti-gH [YC15]

9

YC15 was reformatted as a scFv fragment and combined with Pseudomonas aeruginosa exotoxin A to create an immunotoxin against KSHV-infected cells (Cai & Berger, 2011). YC15 was shown to bind cells expressing gH on the surface using flow cytometry, where binding was sufficient to neutralise gH activity and also induce a cytotoxic effect.

Flow Cytometry, Neutralisation/Blocking

Research Use Only

Monoclonal

YC15

ORF22

ORF22

HHV8GK18_gp26; ORF22

Mouse

IgM

Envelope glycoprotein H

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203