Anti-Glomerular antigen [E5-1]

Absolute Antibody

Anti-Glomerular antigen [E5-1]

9

This antibody displays polyreactive binding to GA, ssDNA, dsDNA and IgG. It does not bind histones or Sm proteins.

The binding specificity of this antibody has been confirmed in ELISA and Western blot analysis (Sekine et al, 2004). Intravenous administration of this antibody to normal mice results in glomerular binding, as revealed by immunofluoescence analysis, suggesting that the production of glomerular-binding autoantibodies by renal mononuclear cells conributes to the developmet of lupus nephritis (Sekine et al, 2004).

ImmunoFluorescence, Western Blot, ELISA

Research Use Only

Monoclonal

E5-1

Mouse

IgG1

Mouse

-20°C,2°C to 8°C

12352203