Anti-Glutaryllysine Mouse mAb

PTM BIO

Anti-Glutaryllysine Mouse mAb

5

Anti-Glutaryllysine Mouse mAb detects proteins post-translationally modified by glutarylation on lysine residues. This pan antibody recognizes GL lysine independent of its surrounding sequences.

Western Blot

WB

Antibody

Research Use Only

Monoclonal

Unconjugated

Mouse

IgG

Lysine glutarylation is a histone post-translational modification (PTM) that has been recently identified through integrated proteomic approaches and elaborate biochemistry analyses. This modification has been shown to be evolutionarily conserved across multiple species of prokaryotes and eukaryotes, and is present in a wide range of proteins, including both histones and non-histone substrates. Lysine glutarylation is a PTM that is regulated by SIRT5 and nutrient availability, and it has been demonstrated to impact various metabolic processes and mitochondrial functions.

Stable for 12 months from date of receipt/reconstitution.

All Species

All

Protein G and immunogen affinity purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203