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anti-GP IIb/IIIa antibody [237]

ARG10091
Arigo Biolaboratories
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetITGA2B
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-GP IIb/IIIa antibody [237]
  • Delivery Days Customer
    23
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    237
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3674
  • Target name
    ITGA2B
  • Target description
    integrin subunit alpha 2b
  • Target synonyms
    alphaIIb protein; BDPLT16; BDPLT2; CD41; CD41B; GP2B; GPalpha IIb; GPIIb; GT; GT1; GTA; HPA3; integrin alpha-IIb; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Human platelet membrane glycoprotein Glycoprotein IIb/IIIa (GP IIb/IIIa) is a dominate receptor on the platelet membrane with very high molecular weight (>200kDa). After the platelet is activated, the GP IIb/IIIa receptor complex changes conformation and binds to fibrinogen in blood circulation with high affinity. The activation of platelets is initiated locally when the endothelial layer is wounded and the platelets are exposed to the collagen underneath the endothelium. The fibrinogen aggregates with platelets when binding to the GP IIb/IIIa receptor on platelets, thus primary haemostasis (Platelet clot) is formed.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203