anti-GPNMB antibody
ARG10645
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Equine, Guinea Pig, Human, Mouse, Rabbit, Rat
TargetGPNMB
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-GPNMB antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID10457
- Target nameGPNMB
- Target descriptionglycoprotein nmb
- Target synonymsglycoprotein (transmembrane) nmb; glycoprotein nmb-like protein; glycoprotein nonmetastatic melanoma protein B; hematopoietic growth factor inducible neurokinin-1 type; HGFIN; NMB; osteoactivin; PLCA3; transmembrane glycoprotein HGFIN; transmembrane glycoprotein NMB
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Canine, Equine, Guinea Pig, Human, Mouse, Rabbit, Rat
- Storage Instruction-20°C
- UNSPSC12352203