anti-GPR2 / CCR10 antibody

Arigo Biolaboratories

anti-GPR2 / CCR10 antibody

23

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

CCR10

C-C motif chemokine receptor 10

CC chemokine receptor 10; C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR-10; chemokine (C-C motif) receptor 10; GPR2; G-protein coupled receptor 2

Rabbit

IgG

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

Hamster, Human, Mouse, Rat

-20°C

12352203