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anti-GRAF / ARHGAP26 antibody

Research Use Only
ARG63557
Arigo Biolaboratories
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Human, Mouse, Rat
TargetARHGAP26
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-GRAF / ARHGAP26 antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23092
  • Target name
    ARHGAP26
  • Target description
    Rho GTPase activating protein 26
  • Target synonyms
    GRAF; GRAF1; GTPase regulator associated with focal adhesion kinase pp125(FAK); oligophrenin-1-like protein; OPHN1L; OPHN1L1; rho GTPase-activating protein 26
  • Host
    Goat
  • Isotype
    IgG
  • Scientific Description
    Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
  • Reactivity
    Bovine, Canine, Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203