Anti-GRP78 Bip

Applied Biological Materials

Anti-GRP78 Bip

9

GRP78 Bip antibody detects endogenous levels of GRP78 Bip protein. Not tested with other proteins

Western Blot, ELISA

Research Use Only

Polyclonal

Rabbit

IgG

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) pointed out that one of these, GRP78 (HSPA5), also referred to as immunoglobulin heavy chain-binding protein (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]

Human

-20°C,2°C to 8°C

12352203