anti-GSK3 alpha (phospho Tyr279) + GSK3 beta (phospho Tyr216) antibody

Arigo Biolaboratories

anti-GSK3 alpha (phospho Tyr279) + GSK3 beta (phospho Tyr216) antibody

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

GSK3B

glycogen synthase kinase 3 beta

glycogen synthase kinase-3 beta; GSK-3 beta; serine/threonine-protein kinase GSK3B

Rabbit

IgG

Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin.

Human

-20°C

12352203