Anti-GST3/GSTP1 Rabbit mAb

PTM BIO

Anti-GST3/GSTP1 Rabbit mAb

5

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin

WB, IHC-P, ICC/IF, FC

Research Use Only

Monoclonal

JRMR-10123-28

Unconjugated

Rabbit

IgG

Glutathione S-transferase P

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the combination of many hydrophobic and electrophilic compounds with reduced glutathione. According to their biochemical, immunological and structural characteristics, mammalian cytoplasmic glutathione S-transferases are divided into eight cytoplasmic soluble subtypes (alfa, kappa, u, pi, σ, thèta, zèta, and omega). Glutathione transferase P1 (GSTpi) is a member of the pi family of the glutathione transferase supergene family. It is highly expressed in the lungs and placenta. It is an important detoxification enzyme that metabolizes toxic compounds in the body and protects cells from Acutely toxic chemical substances play an important role in the attack. GSTP1 is overexpressed in the early stage of carcinogenesis and can be used as a tumor marker in tumor tissues. There are polymorphisms in the GSTP1 gene, and the difference in the activity of the corresponding enzymes in its expression leads to changes in the body's detoxification function, thereby affecting the body's susceptibility to tumors.

Stable for 12 months from date of receipt/reconstitution.

Human

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203