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Anti-HA [CR6261]

Research Use Only
AB02199-10.3-BT
Absolute Antibody
ApplicationsNeutralisation/Blocking
Product group Antibodies
ReactivityVirus
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-HA [CR6261]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody binds hemaglutinin of most group 1 influenza viruses. CR6261 recognizes a highly conserved helical region in the membrane-proximal stem of HA1/HA2.
  • Application Supplier Note
    The antibody neutralizes the virus by blocking conformational rearrangements associated with membrane fusion. CR6261 neutralizes multiple influenza subtypes, including H1, H2, H5, H6, H8, and H9, and protects mice from lethal challenge with H1N1 and H5N1 viruses when administered up to five days post-infection (PMID: 19251591). It is reported that Oseltamivir/Zanamivir may congruously improve the therapeutic efficacy of CR6261 (PMID: 22693576).
  • Applications
    Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CR6261
  • Host
    Human
  • Isotype
    IgG1
  • Reactivity
    Virus
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203