anti-HARS antibody

Arigo Biolaboratories

anti-HARS antibody

23

Western Blot

Research Use Only

Monoclonal

1.1 mg/ml

Unconjugated

HARS1

histidyl-tRNA synthetase 1

CMT2W; HARS; HisRS; histidine translase; histidine--tRNA ligase, cytoplasmic; HRS; Jo-1 antigen; USH3B

Mouse

IgG1

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Human

-20°C

12352203