Anti-HCN4 [N114/10.1]

Absolute Antibody

Anti-HCN4 [N114/10.1]

7

This antibody is specific for the HCN4 antigen. This is a hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions.

The antibody was used in immunofluorescense on the spinal motor neurons and the hippocampus of rats (Hughes et al, 2013; PMID:23357121) (Khurana et al, 2012; PMID:22357864). Immunohistochemistry has been preformed using this antibody on the retinas of rats (Partida et al, 2012; PMID:22281825). Western blot has been preformed on lysate made from rat retinas using this antobody (Partida et al, 2012; PMID:22281825). This antibody can be used for immunopercipitation on rat retinas (Partida et al, 2012; PMID:22281825).

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

IF; IHC; WB; IP

Research Use Only

Monoclonal

N114/10.1

HCN4

hyperpolarization activated cyclic nucleotide gated potassium channel 4

BRGDA8; EIG18; hyperpolarization activated cyclic nucleotide-gated cation channel 4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; SSS2

Human

IgG1

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human, Rat

Human, rat

This antibody was raised by immunising BALB/c mice a fusion protein of GST and amino acids 1019 to 1108 of rat HCN4.

-20°C,2°C to 8°C

12352203