Anti-HCV E1 [5D2]

Absolute Antibody

Anti-HCV E1 [5D2]

9

The antibody is specific for envelope protein 1 of Hepatitis C virus. The antibody recognizes an epitope in E1 represented by aa region 313-326.

The specificity of the Fab format of the antibody was confirmed by ELISA analysis. Further, the antibody was able to neutralize genotype 2a, 1a and 4a of HCV. The affinity of the antibody was measured using peptide IGP 2254 (ITGHRMAWDMMMNWS). Association and dissociation of this peptide to the immobilized antibody was measured using SPR (Kd= 0.06 nM) (US20090104207).

ELISA, Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

5D2

Rabbit

IgG

Genome polyprotein

Virus

-20°C,2°C to 8°C

12352203