Anti-HDAC4 (Phospho-Ser632)

Applied Biological Materials

Anti-HDAC4 (Phospho-Ser632)

9

HDAC4 (phospho-Ser632) antibody detects endogenous levels of HDAC4 only when phosphorylated at serine 632.

Western Blot

Research Use Only

Polyclonal

1 ug/ul

Rabbit

Phosphorylated

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

-20°C,2°C to 8°C

12352203